I have been on Trulicity for 8 weeks now. Side effects were nausea in the first 6 weeks that have subsided. Not ever so bad that it stopped life. I could usually overcome the nausea by eating but I had to mentally push past the nausea. I still lack hunger but I like that effect. My sugar levels have gone from 450 to 120 - 180. I am on the .75 mg and my doctor would like me to take this dose for the next 90 days and then consider increasing it. I am definitely pro Trulicity. Been a life changer for me. I can’t take Wellbutrin. I am allergic to it and most diabetic meds have some form of Metformin in them. My father has been on Trulicity about 2 months longer than me and it seems to be working well for him. He was on 4 meds and insulin. He is off everything except metformin and Trulicity: I only take Trulicity.